Oral pigmented lesions: a pragmatic approach to diagnosis and management Faculty Dental Journal Variations of oral anatomy and common oral lesions Anais Brasileiros de Dermatologia (Portuguese) How Much Are Lipo C Injections in Virginia? Jae Kim, MD Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.